Recurrent infections + anaemia — investigation
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Teaching point — how the wording changes the answer
Recurrent infections + anaemia: think immunodeficiency (serum immunoglobulins), haemoglobinopathy (Hb electrophoresis) or iron deficiency (ferritin). Pick by the dominant clue — recurrent SINO-pulmonary infections favour Ig; microcytic + ethnicity/family favour electrophoresis; pure microcytic with dietary/GI loss favours ferritin.
Q27
Boy, recurrent lung infections + anaemia. Investigation?
Key clue
Recurrent infections prominent
Show answer
Immunoglobulins (vs red cell folate / electrophoresis)
Q210
Young girl, URTI + LRTI, microcytic anaemia. Investigation?
Key clue
Microcytic
Show answer
Ferritin (then TTG / Hb electrophoresis)
Q469
Recurrent chest infections + microcytic anaemia
Key clue
Microcytic
Show answer
Ferritin / iron studies
NA
6-year-old, recurrent chest infection (Hb electrophoresis / CXR / serum Ig)
Key clue
Recurrent infection
Show answer
Hb electrophoresis or serum Ig per dominant clue